Technical Isoprothiolane is a yellow solid with irritating smell. Vapour Pressure:18.8 mPa at 25C.Melting Point: 54--54.5C. Solubility in
water: 54 mg/l (25C). In methanol 1510, ethanol 760, acetone 4060, chloroform 4130, benzene 2770, n-hexane 10 (all in g/l, 25C). Stability Stable to acid, alkali, light and heat.
The acute oral LD50 for mancozeb was 4,500 mg/kg.The
acute dermal (skin) LD50 for mancozeb was greater than 5,000
mg/kg.Mancozeb was mildly irritating to the skin with a primary
irritation score (PIS) of 0.5.Mancozeb caused moderate eye
irritation with a PIS of 2.3.Mancozeb has an acute inhalation to
LC50 of greater than 5.14 mg/L.Mancozeb is used to control
Lophodermium needle cast, Pine gall rust, and Scirrhia brown spot in
conifers and Swiss needle cast in Douglas Fir.
Oral Acute oral LD50 for male rats 1190, female rats 1340. Skin and eye Acute percutaneous LD50 for male and female rats >10 250 mg/kg. Slight eye irritant; not a skin irritant (rabbits). Not a skin sensitiser (guinea pigs). Inhalation LC50 (4 h) for rats >2.7 mg/l. Other Non-mutagenic in the Ames test. In reproduction and teratogenicity studies on rats, no adverse effects were observed.